Thawing fresh frozen plasma(FFP) by waterbath(WB) requires about 30 minutes, which is too slow in emergency situations the risk of bacterial contamination of FFP. To solve these problems, a new thawing method using a microwave oven (MWO) has been
developed. Twenty units of equally divided plasma from 10 units of plasma were frozen, stored at -55℃, and thawed in parallel using microwave oven or waterbath. Coagulation factors, plasma proteins and thawing time were measured. Except for
antithrombin Ⅲ(MWO: 85.2±6.94%, WB:90.8±9.14%, p<0.05), no significant differences were observed in the 18 other coagulation parameters and the plasma proteins studied. Mean thawing me by MWO was 5.9 minutes per 1 unit, 10.4 minutes per 2
units
and
12.5 minutes per 3 units: by WB, it was 19.0, 20.0 and 22.0 minutes, respectively. In conclusion, FFP can be thawed faster using a microwave oven than using 37℃ waterbath and the thawed plasma proteins were generally equivalent to those of FFP
thawed
by waterbath.
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